International Journal of Applied and Basic Medical Research

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 2  |  Issue : 2  |  Page : 102--106

Arthroscopic synovial biopsy in definitive diagnosis of joint diseases: An evaluation of efficacy and precision


Onis Singhal1, Viplesh Kaur1, Shivani Kalhan1, Manish Kumar Singhal1, Anshu Gupta1, YV Machave2 
1 Department of Pathology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India
2 Bharati Vidyapeeth University, Pune, Maharashtra, India

Correspondence Address:
Onis Singhal
R11/10, Raj Nagar, Ghaziabad, Uttar Pradesh - 201 002
India

Context: Arthritis is an important cause of morbidity, presenting as monoarticular or polyarticular lesion. Arthroscopic synovial aspiration and biopsy can help in arriving specific etiological diagnosis. Aim and Objectives: To evaluate the efficacy of arthroscopic synovial biopsy as a diagnostic aid and study the characteristics of synovial fluid in various joint diseases. Materials and Methods: Arthroscopic synovial biopsy along with synovial fluid analysis was studied in 30 of the 50 enrolled cases arthritis. The fluid was subjected to physical, biochemical, and cytological analysis. Results: Both rheumatoid ( n = 14, 28%) and tubercular ( n = 13, 26%) arthritis were found to be more common compared to other etiologies. Next common etiology observed was chronic nonspecific synovitis ( n = 10, 20%). Clinicopathological correlation was seen in 34 out of 50 cases. As a diagnostic tool, synovial biopsy had a sensitivity of 85%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 62%. Conclusion : Arthroscopic synovial biopsy is a simple and easy to perform technique and is an important useful investigative adjunct that may give conclusive diagnosis where clinical diagnosis is equivocal.


How to cite this article:
Singhal O, Kaur V, Kalhan S, Singhal MK, Gupta A, Machave Y V. Arthroscopic synovial biopsy in definitive diagnosis of joint diseases: An evaluation of efficacy and precision.Int J App Basic Med Res 2012;2:102-106


How to cite this URL:
Singhal O, Kaur V, Kalhan S, Singhal MK, Gupta A, Machave Y V. Arthroscopic synovial biopsy in definitive diagnosis of joint diseases: An evaluation of efficacy and precision. Int J App Basic Med Res [serial online] 2012 [cited 2021 Oct 25 ];2:102-106
Available from: https://www.ijabmr.org/article.asp?issn=2229-516X;year=2012;volume=2;issue=2;spage=102;epage=106;aulast=Singhal;type=0