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Year : 2014  |  Volume : 4  |  Issue : 2  |  Page : 117-118

Low serum iron as a possible risk factor for neuroleptic malignant syndrome

Department of Psychiatry, TNMC and B.Y.L Nair Ch. Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Bhushan Subhash Patil
402, Om Balaji Hsg Society, Above Mahesh Hospital, Pune Link Road, Tisgaon Naka, Kalyan (E) - 421 306, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-516X.136800

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Neuroleptic malignant syndrome (NMS) is a rare, but fatal condition characterized by rigidity, fever, dysautonomia and altered consciousness along with elevated serum creatinine phosphokinase levels and leukocytosis. Treatment of NMS includes symptomatic and specific treatment with drugs like bromocriptine may be given. Risk factors for NMS include dehydration, parenteral antipsychotics and high potency antipsychotics. One of the important, but lesser known risk factors for NMS is low serum iron. Pronounced reduction in serum iron suggests that acute phase reactants do have a role in NMS. The present case report focuses on the importance of low serum iron as a risk factor for NMS.

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