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Year : 2011  |  Volume : 1  |  Issue : 1  |  Page : 50-53

Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective

1 Department of Pharmacology, Dr HSJ Institute of Dental Sciences, Chandigarh, India
2 Department of Pharmacology, Government Medical College, Patiala, Punjab, India

Correspondence Address:
Ruchika Nandha
Department of Pharmacology, Dr HSJ Institute of Dental Sciences, PU, Sector 25, Chandigarh, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-516X.81982

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Background: Cutaneous manifestations of adverse drug reactions are a common occurrence and need to be differentiated from other causes of similar manifestations. Active search is essential for identification of these as patients may tend to downplay the causal association between drug use and the subsequent cutaneous manifestation. Purpose: To study the incidence of Cutaneous Adverse Drug Reactions (CADRs) in a tertiary care teaching hospital in North India. Methods: A prospective, observational study was conducted over a period of 6 months; using self-reporting method for selection of cases. The CADRs were graded as definite, possible and probable. Results: During the study period, 91 cases of CADRs were observed. Maximum incidence of CADRs was seen with antimicrobials (48.30%), followed by nonsteroidal anti-inflammatory drugs (21.90%). Maculopapular rash was the most common cutaneous manifestation of ADRs (42.85%). Conclusion: CADRs are a common occurrence and awareness about the same is essential for diagnosis and prevention.

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